Conversion of original units to unified units

Most baseline values found in papers were converted from original units (i.e., mg/ml, number of cells per mm2 of biopsy surface section) to unified units: “pM” for cytokine and “kcell/L” for cell concentration. Formulas for the conversion were implemented in the database.

  • Concept of "Special units" was proposed and corresponding annotation and review forms were implemented in backend of the database. This tool allows us to include into the DB such kind of units for cell subtypes as % of cells_markers_tissue_disease (percent of "parent" cell characterized by particular set of markers) and to recalculate them to unified units whether cells concentration was measured in the annotated article or not. In the first case the concentration of cell subtypes is calculated on the basis of the concentration of "parent" cell available in the article. In the second case the average concentration of the "parent" cell in the particular tissue and disease is taken from the DB.
  • 1. Value [Unified unit] = value [Original unit ]*coeff

    (1.1) Unit ID: % cells over colonic lamina propria area

    Biological meaning of the units: percent of particular cells of total cell count in colonic lamina propria

    Value of conversion coefficient: coeff=1e7 kcell/L/%

    Description: concentration of cells in the intestine epithelium=1e9 kcell/L [ Ann ICRP. 1979;3(1-4):iii. doi: 10.1016/0146-6453(79)90123-4. Report of the task group on reference man. PMID: 20863799]

    (1.2) Unit ID: % of circulating cells

    Biological meaning of the units: percent of particular cells of total circulating cells

    Value of conversion coefficient: coeff=56570000 kcell/L/%

    Description: erythrocytes=5,4e6cells/uL, leucocytes=7e3cells/uL, thrombocytes = 250e3 cells/uL, circulating cells= erythrocytes+leucocytes+thrombocytes = 5,657e6cells/uL= 5,657e9 kcells/L [ Ann ICRP. 1979;3(1-4):iii. doi: 10.1016/0146-6453(79)90123-4. Report of the task group on reference man. PMID: 20863799]

    (1.3) Unit ID: %(Th22+Tc22)

    Biological meaning of the units: percent of particular cells of total cell count of Th22 and Tc22 cells in blood of healthy controls (HC)

    Value of conversion coefficient: coeff=378 kcell/L/%

    Description: meanTh22+meanTc22=30000+7800=37800 kcell/L [averaged on the basis of Cytocon DB]

    (1.4) Unit ID: %B_Blood_AD

    Biological meaning of the units: percent of particular cells of total B cell count in blood of atopic dermatitis (AD) patients

    Value of conversion coefficient: coeff=4830 kcell/L/%

    Description: mean B-cells_Blood_AD=483000 kcell/L [averaged on the basis of Cytocon DB]

    (1.5) Unit ID: %B_Blood_HC

    Biological meaning of the units: percent of particular cells of total B cell count in blood of healthy controls (HC)

    Value of conversion coefficient: coeff=4060 kcell/L/%

    Description: mean B-cells_Blood_HC=406000 kcell/L [averaged on the basis of Cytocon DB]

    (1.6) Unit ID: %B_Blood_Pso

    Biological meaning of the units: percent of particular cells of total B cell count in blood of psoriasis (Pso) patients

    Value of conversion coefficient: coeff=2200 kcell/L/%

    Description: mean B-cells_Blood_HC=220000 kcell/L [averaged on the basis of Cytocon DB]

    (1.7) Unit ID: % CD1a+

    Biological meaning of the units: percent of particular cells of total cell count of CD1a+ cells in non-lesional epidermis of healthy controls (HC)

    Value of conversion coefficient: coeff=290000 kcell/L/%

    Description: mean NLE_HC CD1a+=DC+LC=29e6 kcell/L [averaged on the basis of Cytocon DB]

    (1.8) Unit ID: %CD4+_CCR4+_PL_AP

    Biological meaning of the units: percent of particular cells of total cell count of CD4+CCR4+ cells in blood of asthmatic patients (AP)

    Value of conversion coefficient: coeff=726.51 kcell/L/%

    Description: % of cell count with respect to CD4+ CCR4+ positive T cells (Th2 cell population) measured in blood of asthmatic patients (AP), mean Th2_Blood_Asthma=72651 kcell/L [averaged on the basis of Cytocon DB]

    (1.9) Unit ID: %CD4+_CCR4+_PL_HC

    Biological meaning of the units: percent of particular cells of total cell count of CD4+CCR4+ cells in blood of healthy controls (HC)

    Value of conversion coefficient: coeff=329.22 kcell/L/%

    Description: % of cell count with respect to CD4+ CCR4+ positive T cells (Th2 cell population) measured in PL of HC, mean Th2_PL_HC=32922 kcell/L [averaged on the basis of Cytocon DB]

    (1.10) Unit ID: %CD4+_CD25+_FoxP3+_PL_AP

    Biological meaning of the units: percent of particular cells of total cell count of CD4+CD25+FoxP3+ cells in blood of asthmatic patients (AP)

    Value of conversion coefficient: coeff=1260 kcell/L/%

    Description: % of cell count with respect to CD4+ CD25+ FoxP3+ positive T cells (Treg cell population) measured in blood of Asthmatic patients, mean Treg_Blood_HC=126000 kcell/L [averaged on the basis of Cytocon DB]

    (1.11) Unit ID: %CD4+_CD25+_FoxP3+_PL_HC

    Biological meaning of the units: percent of particular cells of total cell count of CD4+CD25+FoxP3+ cells in blood of healthy controls (HC)

    Value of conversion coefficient: coeff=1260 kcell/L/%

    Description: % of cell count with respect to CD4+ CD25+ FoxP3+ positive T cells (Treg cell population) measured in blood of HC, mean Treg_Blood_HC=126000 kcell/L [averaged on the basis of Cytocon DB]

    (1.12) Unit ID: %CD4+_IL4+_PL_AP

    Biological meaning of the units: percent of particular cells of total cell count of CD4+IL4+ cells in blood of asthmatic patients (AP)

    Value of conversion coefficient: coeff=726.51 kcell/L/%

    Description: % of cell count with respect to CD4+ IL4+ positive T cells (Th2 cell population) measured in blood of AP, mean Th2_Blood_Asthma=72651 kcell/L [averaged on the basis of Cytocon DB]

    (1.13) Unit ID: %CD4+_IL4+_PL_HC

    Biological meaning of the units: percent of particular cells of total cell count of CD4+IL4+ cells in blood of healthy controls (HC)

    Value of conversion coefficient: coeff=329.22 kcell/L/%

    Description: % of cell count with respect to CD4+ IL4+ positive T cells (Th2 cell population) measured in blood of HC, mean Th2_PL_HC=32922 kcell/L [averaged on the basis of Cytocon DB]

    (1.14) Unit ID: %CD4+_PL_AP

    Biological meaning of the units: percent of particular cells of total cell count of CD4+ cells in blood of asthmatic patients (AP)

    Value of conversion coefficient: coeff=9160 kcell/L/%

    Description: % of cell count with respect to CD4+ positive T cells (Th cell population) measured in blood of asthmatic patient (AP), mean Th_PL_AP=916000kcells/L [averaged on the basis of Cytocon DB]

    (1.15) Unit ID: %CD4+_PL_HC

    Biological meaning of the units: percent of particular cells of total cell count of CD4+ cells in blood of healthy controls (HC)

    Value of conversion coefficient: coeff=7920 kcell/L/%

    Description: % of cell count with respect to CD4+ positive T cells (Th cell population) measured in blood of HC, mean Th_PL_HC=792e3kcells/L [averaged on the basis of Cytocon DB] ,

    (1.16) Unit ID: %CD45+

    Biological meaning of the units: percent of particular cells of total cell count of CD45+ cells in blood of healthy controls (HC)

    Value of conversion coefficient: coeff=7e4 kcell/L/%

    Description: % of leukocytes_PL_HC, mean leukocytes_PL_HC=7e6 kcells/L [averaged on the basis of Cytocon DB]

    (1.17) Unit ID: %CD56+_PL_AP

    Biological meaning of the units: percent of particular cells of total cell count of CD56+ cells in blood of asthmatic patients (AP)

    Value of conversion coefficient: coeff= 2797.2 kcell/L/%

    Description: % of cell count with respect to CD56+ positive lymphocytes (NK cell population) measured in blood of AP, NK_Blood_HC=279720 kcell/L [averaged on the basis of Cytocon DB]

    (1.18) Unit ID: %CD56+_PL_HC

    Biological meaning of the units: percent of particular cells of total cell count of CD56+ cells in blood of healthy controls (HC)

    Value of conversion coefficient: coeff= 2797.2 kcell/L/%

    Description: % of cell count with respect to CD56+ positive lymphocytes (NK cell population) measured in blood of HC, NK_Blood_HC=279720 kcell/L [averaged on the basis of Cytocon DB]

    (1.19) Unit ID: %CD8+_PL_AP

    Biological meaning of the units: percent of particular cells of total cell count of CD8+ cells in blood of asthmatic patients (AP)

    Value of conversion coefficient: coeff= 4460 kcell/L/%

    Description: % of cell count with respect to CD8+ positive T cells (Tc cell population) measured in blood of asthmatic patient (AP), mean Tc_PL_HC=446000kcell/L [averaged on the basis of Cytocon DB]

    (1.20) Unit ID: %CD8+_PL_HC

    Biological meaning of the units: percent of particular cells of total cell count of CD8+ cells in blood of healthy controls (HC)

    Value of conversion coefficient: coeff= 4460 kcell/L/%

    Description: % of cell count with respect to CD8+ positive T cells (Tc cell population) measured in blood of HC, mean Tc_PL_HC=446000kcell/L [averaged on the basis of Cytocon DB]

    (1.21) Unit ID: %cells_NLE

    Biological meaning of the units: percent of particular cells of total cell count of non-lesional epidermis

    Value of conversion coefficient: coeff=2e5 kcell/L/%

    Description: % of cells in non-lesional epidermis, total cells concentration in epidermis=20e6cells/ml=2e7kcells/L [averaged on the basis of Cytocon DB] ,

    (1.22) Unit ID: %DC

    Biological meaning of the units: percent of particular cells of total cell count of dendritic cells (DC) in non-lesional epidermis of healthy controls (HC)

    Value of conversion coefficient: coeff= 59470 kcell/L/%

    Description: %DC_NLE_HC, mean DC_NLE_DC=5947000 kcell/L [averaged on the basis of Cytocon DB]

    (1.23) Unit ID: %DC_NLD_HC

    Biological meaning of the units: percent of particular cells of total cell count of dendritic cells (DC) in non-lesional dermis of healthy controls (HC)

    Value of conversion coefficient: coeff= 6400 kcell/L/%

    Description: mean DC_NLD_DC=640000 kcell/L [averaged on the basis of Cytocon DB]

    (1.24) Unit ID: %EC

    Biological meaning of the units: percent of particular cells of total cell count of endothelial cells (EC) in non-lesional epidermis of healthy controls (HC)

    Value of conversion coefficient: coeff= 200000 kcell/L/%

    Description: %EC_NLE_HC, total cells concentration in epidermis=20e6cells/ml=2e7kcells/L [averaged on the basis of Cytocon DB],

    (1.25) Unit ID: %Foxp3+Treg_CAC_31048714

    Biological meaning of the units: percent of particular cells of total cell count of Foxp3+Treg cells in tumor specimen of colitis-associated cancer

    Value of conversion coefficient: coeff= 35000 kcell/L/%

    Description: Foxp3+Treg_CAC_31048714=3500000kcell/L [31048714]

    (1.26) Unit ID: %Foxp3+Treg_sporadicCRC_31048714

    Biological meaning of the units: percent of particular cells of total cell count of Foxp3+Treg cells in tumor specimen of sporadic colorectal cancer

    Value of conversion coefficient: coeff= 120000 kcell/L/%

    Description: Foxp3+Treg_sporadicCRC_31048714=12000000kcell/L [31048714]

    (1.27) Unit ID: %ILC

    Biological meaning of the units: percent of particular cells of total cell count of innate lymphoid cells (ILC) in blood of HC

    Value of conversion coefficient: coeff= 2820 kcell/L/%

    Description: ILC=ILC2+NK=282000 kcell/L [averaged on the basis of Cytocon DB]

    (1.28) Unit ID: %LC

    Biological meaning of the units: percent of particular cells of total cell count of Langerhans cells (LC) in non-lesional epidermis of healthy controls (HC)

    Value of conversion coefficient: coeff= 234000 kcell/L/%

    Description: mean LC_NLE_HC=23400000 kcell/L [averaged on the basis of Cytocon DB]

    (1.29) Unit ID: %LC_NLD_HC

    Biological meaning of the units: percent of particular cells of total cell count of Langerhans cells (LC) in non-lesional dermis of healthy controls (HC)

    Value of conversion coefficient: coeff= 3810 kcell/L/%

    Description: mean LC_NLD_HC=381000 kcell/L [averaged on the basis of Cytocon DB]

    (1.30) Unit ID: %LYMPH_Blood_AD

    Biological meaning of the units: percent of particular cells of total cell count of lymphocytes in blood of atopic dermatitis (AD) patients

    Value of conversion coefficient: coeff= 17750 kcell/L/%

    Description: Lymphocytes_Blood_AD=1775000 kcell/L [averaged on the basis of Cytocon DB]

    (1.31) Unit ID: %LYMPH_Blood_HC

    Biological meaning of the units: percent of particular cells of total cell count of lymphocytes in blood of healthy controls (HC)

    Value of conversion coefficient: coeff= 32000 kcell/L/%

    Description: Lymphocytes_Blood_HC=3200000 kcell/L [averaged on the basis of Cytocon DB]

    (1.32) Unit ID: %LYMPH_Blood_Pso

    Biological meaning of the units: percent of particular cells of total cell count of lymphocytes in blood of Psoriasis (Pso) patients

    Value of conversion coefficient: coeff= 26000 kcell/L/%

    Description: Lymphocytes_Blood_Pso=2600000 kcell/L [averaged on the basis of Cytocon DB]

    (1.33) Unit ID: %LYMPH_PL_AP

    Biological meaning of the units: percent of particular cells of total cell count of lymphocytes in blood of asthmatic patients (AP)

    Value of conversion coefficient: coeff= 22000 kcell/L/%

    Description: % of cell count with respect to lymphocytes measured in blood of asthmatic patients (AP), mean LYMPH_PL_AP=2,2e6 kcells/L [Res J Allergy Immunol, 2016, V.1,1, AC Gungen, Yu. Aydemir. The correlation between asthma disease and neutrophil to lymphocyte ratio ]

    (1.34) Unit ID: %LYMPH_PL_HC

    Biological meaning of the units: percent of particular cells of total cell count of lymphocytes in blood of healthy controls (HC)

    Value of conversion coefficient: coeff= 21600 kcell/L/%

    Description: % of lymphocytes in blood of HC, mean LYMPH_PL_HC=21,6e5kcells/L [averaged on the basis of Cytocon DB],

    (1.35) Unit ID: %MC

    Biological meaning of the units: percent of particular cells of total cell count of mast cells (MC) in non-lesional dermis of healthy controls (HC)

    Value of conversion coefficient: coeff= 13500 kcell/L/%

    Description: %MC_NLD_HC, mean MC_NLD_HC=1350000 kcell/L [averaged on the basis of Cytocon DB]

    (1.36) Unit ID: %MON

    Biological meaning of the units: percent of particular cells of total cell count of monocytes (MON) in blood of healthy controls (HC)

    Value of conversion coefficient: coeff= 4000 kcell/L/%

    Description: %Mon_PL_HC, mean Mon_PL_HC=400000kcell/L [averaged on the basis of Cytocon DB]

    (1.37) Unit ID: %PBMC

    Biological meaning of the units: percent of particular cells of total cell count of PBMC (peripheral blood mononuclear cells) in blood of healthy controls (HC)

    Value of conversion coefficient: coeff= 25600 kcell/L/%

    Description: %PBMC_PL_HC, mean PBMC= mean LYMPH+meanMON=2560000 kcell/L [averaged on the basis of Cytocon DB]

    (1.38) Unit ID: %PD-L1+cell_CAC_31048714

    Biological meaning of the units: percent of particular cells of total cell count of PD-L1+ cells in tumor specimen of colitis-associated cancer

    Value of conversion coefficient: coeff= 220000 kcell/L/%

    Description: PD-L1+cell_CAC_31048714=22000000kcell/L [31048714]

    (1.39) Unit ID: %PD-L1+cell_sporadicCRC_31048714

    Biological meaning of the units: percent of particular cells of total cell count of PD-L1+ cells in tumor specimen of sporadic colorectal cancer

    Value of conversion coefficient: coeff= 1540000 kcell/L/%

    Description: PD-L1+cell_sporadicCRC_31048714=154000000kcell/L [31048714]

    (1.40) Unit ID: %T_blood_AD

    Biological meaning of the units: percent of particular cells of total cell count of T cells in blood of atopic dermatitis (AD) patients

    Value of conversion coefficient: coeff= 26515.83 kcell/L/%

    Description: % of T-cells in blood of AD patients, mean T_blood_AD=2651583kcells/L [averaged on the basis of Cytocon DB],

    (1.41) Unit ID: %T_blood_HC

    Biological meaning of the units: percent of particular cells of total cell count of T cells in blood of healthy controls (HC)

    Value of conversion coefficient: coeff= 17591.47 kcell/L/%

    Description: % of T cells in blood of HC, mean T_blood_HC=1759147kcells/L [averaged on the basis of Cytocon DB],

    (1.42) Unit ID: %T_blood_Pso

    Biological meaning of the units: percent of particular cells of total cell count of T cells in blood of Psoriasis (Pso) patients

    Value of conversion coefficient: coeff= 16156.8 kcell/L/%

    Description: % of T-cells in blood of Psoriasis patients, mean T_blood_Pso=1615680kcells/L [averaged on the basis of Cytocon DB] ,

    (1.43) Unit ID: %T_LS_AD

    Biological meaning of the units: percent of particular cells of total cell count of T cells in lesional skin of atopic dermatitis (AD) patients

    Value of conversion coefficient: coeff= 11618.95 kcell/L/%

    Description: % of T-cells in lesional skin of AD patients, mean T_LS_AD=1161895 kcells/L [averaged on the basis of Cytocon DB] ,

    (1.44) Unit ID: %T_LS_Pso

    Biological meaning of the units: percent of particular cells of total cell count of cells in lesional skin of Psoriasis (Pso) patients

    Value of conversion coefficient: coeff= 179916.76 kcell/L/%

    Description: % of T-cells in lesional skin of psoriasis patients, mean T_LS_Pso=17991676 kcells/L [averaged on the basis of Cytocon DB],

    (1.45) Unit ID: %T_NLS_AD

    Biological meaning of the units: percent of particular cells of total cell count of T cells in non-lesional skin of atopic dermatitis (AD) patients

    Value of conversion coefficient: coeff= 19000 kcell/L/%

    Description: T_NLS_AD=1900000 kcell/L [averaged on the basis of Cytocon DB]

    (1.46) Unit ID: %T_NLS_Cutaneous Lupus Erythematosus

    Biological meaning of the units: percent of particular cells of total cell count of T cells in in non-lesional skin of SLE patients

    Value of conversion coefficient: coeff= 19000 kcell/L/%

    Description: T_NLS_AD=1900000 kcell/L [averaged on the basis of Cytocon DB] , no data for the disease

    (1.47) Unit ID: %T_NLS_Dermatomyositis

    Biological meaning of the units: percent of particular cells of total cell count of T cells in in non-lesional skin of dermatomyositis patients

    Value of conversion coefficient: coeff= 19000 kcell/L/%

    Description: T_NLS_AD=1900000 kcell/L [averaged on the basis of Cytocon DB] , no data for the disease

    (1.48) Unit ID: %T_NLS_Pso

    Biological meaning of the units: percent of particular cells of total cell count of T cells in in non-lesional skin of Psoriasis (Pso) patients

    Value of conversion coefficient: coeff= 19000 kcell/L/%

    Description: T_NLS_AD=1900000 kcell/L [averaged on the basis of Cytocon DB] , no data for the disease

    (1.49) Unit ID: %TBC

    Biological meaning of the units: percent of particular cells of total blood cell count

    Value of conversion coefficient: coeff= 55670000 kcell/L/%

    Description: % of total blood cells, erythrocytes=5,4e6cells/uL, leucocytes=7e3cells/uL, thrombocytes = 250000 cells/uL, TBC=erythrocytes+leucocytes+thrombocytes = 5,567e6cells/uL= 5,567e9kcells/L [ Ann ICRP. 1979;3(1-4):iii. doi: 10.1016/0146-6453(79)90123-4. Report of the task group on reference man. PMID: 20863799]

    (1.50) Unit ID: %Tc_LS_AD

    Biological meaning of the units: percent of particular cells of total cell count of Tc cells in lesional skin of atopic dermatitis (AD) patients

    Value of conversion coefficient: coeff= 3960 kcell/L/%

    Description: Tc_LS_AD=396000 kcell/L [averaged on the basis of Cytocon DB]

    (1.51) Unit ID: %Tc_LS_Pso

    Biological meaning of the units: percent of particular cells of total cell count of Tc cells in lesional skin of Psoriasis (Pso) patients

    Value of conversion coefficient: coeff= 3960 kcell/L/%

    Description: Tc_LS_AD=396000 kcell/L [averaged on the basis of Cytocon DB] , no data for Psoriasis

    (1.52) Unit ID: %Th_LD_AD

    Biological meaning of the units: percent of particular cells of total cell count of Th cells in lesional dermis of atopic dermatitis (AD) patients

    Value of conversion coefficient: coeff= 23632.45 kcell/L/%

    Description: % of Th-cells in lesional dermis of AD patients, mean Th_LD_AD=2363245kcells/L [averaged on the basis of Cytocon DB],

    (1.53) Unit ID: %Th_NLD_AD

    Biological meaning of the units: percent of particular cells of total cell count of Th cells in non-lesional dermis of atopic dermatitis (AD) patients

    Value of conversion coefficient: coeff= 6641.83 kcell/L/%

    Description: % of Th cells in non-lesional dermis of AD patients, mean Th_NLD_AD=664183kcells/L [averaged on the basis of Cytocon DB],

    (1.54) Unit ID: %Th_NLD_HC

    Biological meaning of the units: percent of particular cells of total cell count of Th cells in non-lesional dermis of healthy controls (HC)

    Value of conversion coefficient: coeff= 547.84 kcell/L/%

    Description: % of Th-cells in non-lesional dermis of healthy controls, mean Th_NLD_HC=54784kcells/L [averaged on the basis of Cytocon DB] ,

    (1.55) Unit ID: %Th_PL_AD

    Biological meaning of the units: percent of particular cells of total cell count of Th cells in blood of healthy controls (HC)

    Value of conversion coefficient: coeff= 320000 kcell/L/%

    Description: % of Th-cells in blood of AD patients, mean Th_PL_AD=320e5kcells/L [averaged on the basis of Cytocon DB],

    (1.56) Unit ID: %Th1

    Biological meaning of the units: percent of particular cells of total cell count of Th1 cells in blood of healthy controls (HC)

    Value of conversion coefficient: coeff= 3330 kcell/L/%

    Description: %Th1_PL_HC, mean Th1_PL_HC = 333000kcell/L [averaged on the basis of Cytocon DB]

    (1.57) Unit ID: %Th1_Blood_HC

    Biological meaning of the units: percent of particular cells of total cell count of Th1 cells in blood of healthy controls (HC)

    Value of conversion coefficient: coeff= 3880 kcell/L/%

    Description: mean Th1_Blood_HC=388000kcell/L [averaged on the basis of Cytocon DB]

    (1.58) Unit ID: %Treg

    Biological meaning of the units: percent of particular cells of total cell count of Treg cells in blood of healthy controls (HC)

    Value of conversion coefficient: coeff= 1260 kcell/L/%

    Description: %Treg_Blood_HC, mean Treg_Blood_HC=126000 kcell/L [averaged on the basis of Cytocon DB]

    (1.59) Unit ID: %WBC_Blood_AD

    Biological meaning of the units: percent of particular cells of total cell count of leukocytes in blood of atopic dermatitis (AD) patients

    Value of conversion coefficient: coeff= 83000 kcell/L/%

    Description: WBC_Blood_AD=8300000 kcell/L [averaged on the basis of Cytocon DB]

    (1.60) Unit ID: %WBC_Blood_HC

    Biological meaning of the units: percent of particular cells of total cell count of leukocytes in blood of healthy controls (HC)

    Value of conversion coefficient: coeff= 7e4 kcell/L/%

    Description: % of white blood cells, mean WBC_Blood_HC=7e6 kcell/L [averaged on the basis of Cytocon DB]

    (1.61) Unit ID: 1E3*cells/mm3

    Value of conversion coefficient: coeff= 1e6

    Description: value [1E3*cells/mm3] = value * 1e6 [kcell/L]

    (1.62) Unit ID: 1E3*cells/uL

    Value of conversion coefficient: coeff= 1e6

    Description: value [1E3*cells/uL] = value * 1e6 [kcell/L]

    (1.63) Unit ID: 1E3/g

    Value of conversion coefficient: coeff= 1e3

    Description: 1e3 cells/g, 1g=1mL, value [1E3/g] = value * 1e3 [kcell/L]

    (1.64) Unit ID: 1E3/ml

    Value of conversion coefficient: coeff= 1e3

    Description: 1e3 cells/ml, value [1E3/ml] = value * 1e3 [kcell/L]

    (1.65) Unit ID: 1E4*cells/mm3

    Value of conversion coefficient: coeff= 1e7

    Description: in blood, value [1E4*cells/mm3] = value * 1e7 [kcell/L]

    (1.66) Unit ID: 1E6 cells/ml

    Value of conversion coefficient: coeff= 1e6

    Description: value [1E6 cells/ml] = value * 1e6 [kcell/L]

    (1.67) Unit ID: 1E6*cells/L

    Value of conversion coefficient: coeff= 1e3

    Description: value [1E6*cells/L] = value * 1e3 [kcell/L]

    (1.68) Unit ID: 1E6*cells/mm3

    Value of conversion coefficient: coeff= 1e9

    Description: value [1E6*cells/mm3] = value * 1e9 [kcell/L]

    (1.69) Unit ID: 1E9*cells/L

    Value of conversion coefficient: coeff= 1e6

    Description: value [1E9*cells/L] = value * 1e6 [kcell/L]

    (1.70) Unit ID: 1E9/L

    Value of conversion coefficient: coeff= 1e6

    Description: 1e9 cells/L, value [1E9/L] = value * 1e6 [kcell/L]

    (1.71) Unit ID: cells in BM/kg BW

    Value of conversion coefficient: coeff= 0.061

    Description: cells in bone marrow, BM ISF volulme=0,4 BM volume (assumption - taken from dermis), BM Volume=2,88L [ Ann ICRP. 1979;3(1-4):iii. doi: 10.1016/0146-6453(79)90123-4. Report of the task group on reference man. PMID: 20863799], so BM ISF Volume=0,4*2,88L=1,152L, n cells in BM/kg BW=n cells* 70 kg/1,152L=n*0,061 kcell/L

    (1.72) Unit ID: cells in PL/kg BW

    Value of conversion coefficient: coeff= 0.025

    Description: cells in blood, n*70kg/2,75L plasma=n*0.025kcell/L, where V(blood)=5L, V(Plasma)=55%V(blood)=0.55*5=2.75L

    (1.73) Unit ID: cells/ml

    Value of conversion coefficient: coeff= 1

    Description: value [cells/ml] = value * 1 [kcell/L]

    (1.74) Unit ID: cells/mm3

    Value of conversion coefficient: coeff=1e3

    Description: value [cells/mm3] = value * 1e3 [kcell/L]

    (1.75) Unit ID: cells/uL

    Value of conversion coefficient: coeff=1e3

    Description: value [cells/uL] = value * 1e3 [kcell/L]

    (1.76) Unit ID: Gcell/L

    Value of conversion coefficient: coeff=1e6

    Description: value [Gcell/L] = value * 1e6 [kcell/L]

    (1.77) Unit ID: kcells/uL

    Value of conversion coefficient: coeff=1e6

    Description: value [kcells/uL] = value * 1e6 [kcell/L]

    (1.78) Unit ID: mM

    Value of conversion coefficient: coeff=1e9

    Description: value [mM] = value * 1e9 [pM]

    (1.79) Unit ID: mmol/L

    Value of conversion coefficient: coeff=1e9

    Description: value [ mmol/L] = value * 1e9 [pM]

    (1.80) Unit ID: nM

    Value of conversion coefficient: coeff=1e3

    Description: value [nM] = value * 1e3 [pM]

    (1.81) Unit ID: pmol/ml

    Value of conversion coefficient: coeff=1e3

    Description: value [pmol/ml] = value * 1e3 [pM]

    (1.82) Unit ID: Ratio to cholesteryl ester_Lymph_HC

    Biological meaning of the units: Ratio of particular molecule concentration to cholesteryl ester concentration in lymph of HC

    Value of conversion coefficient: coeff=5e8

    Description: cholesteryl ester_Lymph_HC=0.50 +- 0.02 mM mean + sem [PMID 10946020]

    (1.83) Unit ID: Ratio to cholesteryl ester_Plasma_HC

    Biological meaning of the units: Ratio of particular molecule concentration to cholesteryl ester concentration in plasma of HC

    Value of conversion coefficient: coeff=3,38e9

    Description: cholesteryl ester_Plasma_HC=3.38 +- 0.11 mM mean + sem [10946020]

    (1.84) Unit ID: Ratio to Non-HDL cholesterol_Plasma_HC

    Biological meaning of the units: Ratio of particular molecule concentration to Non-HDL cholesterol concentration in plasma of HC

    Value of conversion coefficient: coeff=3,58e9

    Description: Non-HDL cholesterol_Plasma_HC=Total cholesterol - HDL-cholesterol = 4.76-1.18 = 3.58 mM [10946020]

    (1.85) Unit ID: uM

    Value of conversion coefficient: coeff=1e6

    Description: value [uM] = value * 1e6 [pM]

    2. Value [Unified unit] = value [Original unit] *coeff/Mw

    (2.1) Unit ID: g/dL

    Value of conversion coefficient : coeff=1e10, Mw [kDa]

    Description: value [g/dL] = value * 1e10/Mw [pM]

    (2.2) Unit ID: IU/ml-IFNg

    Value of conversion coefficient : coeff=200, Mw=17,15 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (2.3) Unit ID: IU/ml-IgE

    Value of conversion coefficient : coeff=2,4e6, Mw=190 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (2.4) Unit ID: kU/L-IgE

    Value of conversion coefficient : coeff=2,4e6, Mw=190 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (2.5) Unit ID: kU/L-IL10

    Value of conversion coefficient : coeff=5000, Mw=20,52 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (2.6) Unit ID: kU/L-IL4

    Value of conversion coefficient : coeff=100, Mw=17,49 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (2.7) Unit ID: kU/ml-IgE

    Value of conversion coefficient : coeff=2,4e9, Mw=190 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (2.8) Unit ID: mg%

    Biological meaning of the units : the mass (in milligrams) of a molecule in 100 milliliters of solution (e.g., blood).

    Value of conversion coefficient : coeff=1e7, Mw [kDa] is taken for a particular molecule

    Description: mg%=mg/100ml=mg/dL

    (2.9) Unit ID: mg/dL

    Value of conversion coefficient : coeff=1e7, Mw [kDa] is taken for a particular molecule

    Description: value [mg/dL] = value * 1e7/Mw [pM]

    (2.10) Unit ID: mg/L

    Value of conversion coefficient : coeff=1e6, Mw [kDa] is taken for a particular molecule

    Description: value [mg/L] = value * 1e6/Mw [pM]

    (2.11) Unit ID: mg/mL

    Value of conversion coefficient : coeff=1e9, Mw [kDa] is taken for a particular molecule

    Description: value [mg/mL] = value * 1e9/Mw [pM]

    (2.12) Unit ID: ng/L

    Value of conversion coefficient : coeff=1, Mw [kDa] is taken for a particular molecule

    Description: value [ng/L] = value * 1/Mw [pM]

    (2.13) Unit ID: ng/ml

    Value of conversion coefficient : coeff=1000, Mw [kDa] is taken for a particular molecule

    Description: value [ng/ml] = value * 1000/Mw [pM]

    (2.14) Unit ID: ng/mL

    Value of conversion coefficient : coeff=1000, Mw [kDa] is taken for a particular molecule

    Description: value [ng/mL] = value * 1000/Mw [pM]

    (2.15) Unit ID: ng/ml_SBF

    Biological meaning of the units : concentration of a molecule in 1ml of suction blister fluids

    Value of conversion coefficient : coeff=1300, Mw [kDa] is taken for a particular molecule

    Description: SBF – suction blister fluids, value [ng/ml_SBF] = value * 1300/Mw [pM]

    (2.16) Unit ID: pg/g

    Value of conversion coefficient : 1g=1mL, coeff=1, Mw [kDa] is taken for a particular molecule

    Description: value [pg/g] = value * 1/Mw [pM]

    (2.17) Unit ID: pg/mg

    Value of conversion coefficient : 1mg=1uL, coeff=1e3, Mw [kDa] is taken for a particular molecule

    Description: value [pg/mg] = value * 1e3/Mw [pM]

    (2.18) Unit ID: pg/mL

    Value of conversion coefficient : coeff=1, Mw [kDa] is taken for a particular molecule

    Description: value [pg/mL] = value * 1/Mw [pM]

    (2.19) Unit ID: pg/ml

    Value of conversion coefficient : coeff=1, Mw [kDa] is taken for a particular molecule

    Description: value [pg/ml] = value * 1/Mw [pM]

    (2.20) Unit ID: pg/ml_skin

    Biological meaning of the units : mass of a molecule in 1 ml of interstitial fluid of skin

    Value of conversion coefficient : coeff=2,5, Mw [kDa] is taken for a particular molecule

    Description: value [pg/ml_skin] = value * 2,5/Mw [pM]

    (2.21) Unit ID: pg/ml_ISF

    Value of conversion coefficient : coeff=1, Mw [kDa] is taken for a particular molecule

    Description: in interstitial fluid of skin, value [pg/ml_ISF] = value * 1/Mw [pM]

    (2.22) Unit ID: pg/ml_SBF

    Value of conversion coefficient : coeff=1.3, Mw [kDa] is taken for a particular molecule

    Description: in suction blister fluids, value [pg/ml_SBF] = value * 1.3/Mw [pM]

    (2.23) Unit ID: U/ml-IFNa

    Value of conversion coefficient : coeff=9,

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (2.24) Unit ID: U/ml-IFNg

    Value of conversion coefficient : coeff=200, Mw=17,15 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (2.25) Unit ID: U/ml-IgE

    Value of conversion coefficient : coeff=2,4e6, Mw=190 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (2.26) Unit ID: U/ml-IL5

    Value of conversion coefficient : coeff=100, Mw=15,24 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (2.27) Unit ID: U/ml-IL6

    Value of conversion coefficient : coeff=1000, Mw=23,72 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (2.27) Unit ID: U/ml-TNFa

    Value of conversion coefficient : coeff=13, Mw=25,64 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (2.28) Unit ID: ug/L

    Value of conversion coefficient : coeff=1e3, Mw [kDa] is taken for a particular molecule

    Description: value [ug/L] = value * 1e3/Mw [pM]

    (2.28) Unit ID: ug/ml

    Value of conversion coefficient : coeff=1e6, Mw [kDa] is taken for a particular molecule

    Description: value [ug/ml] = value * 1e6/Mw [pM]

    (2.29) Unit ID: uIU/mL-Insulin

    Value of conversion coefficient : coeff=7,175, Mw=5,734 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    3. Value [Unified unit] = value [Original unit] ^1,5*coeff

    (3.1) Unit ID: cells/mm dermis

    Biological meaning of the units : cells in dermis calculated on 1mm of basement membrane of epidermis

    Value of conversion coefficient : coeff= 578.704,

    Description: cells in dermis calculated on 1mm of basement membrane of epidermis, C (in total dermis tissue volume)=(n/(a*b))^(3/2)=n^(3/2)*578.704 [kcells/L], Where a=1mm, b=1.44mm, (HS dermis thickness [PMID: 20863799])

    (3.2) Unit ID: cells/mm epidermis

    Biological meaning of the units : cells in epidermis calculated on 1mm of basement membrane of epidermis

    Value of conversion coefficient : coeff=40355,

    Description: cells in epidermis calculated on 1mm of basement membrane of epidermis, C (in total epidermis volume)=(n/(a*b))^(3/2)=n^(3/2)*40355 [kcells/L] Where a=1mm; b=0,085mm (HS epidermis thickness [ Ann ICRP. 1979;3(1-4):iii. doi: 10.1016/0146-6453(79)90123-4. Report of the task group on reference man. PMID: 20863799])

    (3.3) Unit ID: cells/mm of jejunal epithelium

    Biological meaning of the units : cells in jejunal epithelium calculated on 1mm of basement membrane of jejunal epithelium

    Value of conversion coefficient : coeff=451060,

    Description: cells in jejunal epithelium calculated on 1mm of basement membrane of jejunal epithelium, C (in total jejunal epithelium volume)=(n/(a*b))^(3/2)=n^(3/2)*451060 [kcells/L] Where a=1mm; b=0,017mm (HS jejunal epithelium thickness [ Ann ICRP. 1979;3(1-4):iii. doi: 10.1016/0146-6453(79)90123-4. Report of the task group on reference man. PMID: 20863799])

    (3.4) Unit ID: cells/mm2 bronchial tissue

    Biological meaning of the units : cells in 1mm2 of bronchial tissue biopsy specimen

    Value of conversion coefficient : coeff=1000,

    Description: cells in bronchial tissue, C (in total bronchial tissue volume) = (n/(a*b))^(3/2) = n^(3/2)*1000 [kcells/L], Where a*b=1mm2

    (3.5) Unit ID: cells/mm2 dermis

    Biological meaning of the units : cells in 1mm2 of dermis biopsy specimen

    Value of conversion coefficient : coeff=1000,

    Description: Concentration of cells (in total dermis volume)=(n/(a*b))^1,5=n^1,5*1000 [kcells/L], Where a*b=1mm2

    (3.6) Unit ID: cells/mm2 epidermis

    Biological meaning of the units : cells in 1mm2 of epidermis biopsy specimen

    Value of conversion coefficient : coeff=1000,

    Description: cells in ISF of epidermis, C (in total epidermis volume) = (n/(a*b))^(3/2) = n^(3/2)*1000 [kcells/L], Where a*b=1mm2

    (3.7) Unit ID: cells/mm2 of jejunal lamina propria

    Biological meaning of the units : cells in 1mm2 of jejunal lamina propria biopsy specimen

    Value of conversion coefficient : coeff=1000,

    Description: cells in total volume of jejunum, C = (n/(a*b))^(3/2) = n^(3/2)*1000 [kcells/L], Where a*b=1mm2

    (3.8) Unit ID: cells/mm2_tissue

    Biological meaning of the units : cells in 1mm2 of tissue biopsy specimen

    Value of conversion coefficient : coeff=1000,

    Description: cells in total volume of tissue, C (in tissue volume) = (n/(a*b))^(3/2) = n^(3/2)*1000 [kcells/L], Where a*b=1mm2

    (3.9) Unit ID: CPF_Nikon_C2_x250 dermis

    Biological meaning of the units : cells per field of Nikon microscope magnification ratio 250

    Value of conversion coefficient : coeff=2500,

    Description: cells per field d=18mm, C (in dermis ISF) = (n/(Sfield))^(3/2)/0,4 = n^(3/2)*2500 [kcell/L], Where Sfield = Field of vision (circle with d=18mm)/(magnification ratio (400 or 250))=pi*(9mm)^2/250=1mm2

    (3.10) Unit ID: CPF_Nikon_C2_x400 dermis

    Biological meaning of the units : cells per field of Nikon microscope, magnification ratio 400

    Value of conversion coefficient : coeff=4900,

    Description: cells per field d=18mm, C (in dermis ISF) = (n/(Sfield))^(3/2)/0,4 = n^(3/2)*4900 [kcell/L], Where Sfield = Field of vision (circle with d=18mm)/(magnification ratio (400 or 250))=pi*(9mm)^2/400=0,636mm2

    (3.11) Unit ID: CPF_Zeiss_Axioscope_2_x400 dermis

    Biological meaning of the units : cells per field of Zeiss Axioscope, magnification ratio 400

    Value of conversion coefficient : coeff=2500,

    Description: C (in dermis ISF)=(n/(Sfield))^(3/2)/0,4=n^(3/2)*2500 [kcell/L], Sfield = Field of vision (circle with d=23mm)/(magnification ratio 400)=pi*(11,5mm)^2/400=1mm2, Dermis ISF volume (% of Dermis volume) = 40% [21722573]

    (3.12) Unit ID: CPS 4mm dermis

    Biological meaning of the units : cells per section 4mm biopsies dermis

    Value of conversion coefficient : coeff=181,

    Description: cells per section 4mm biopsies dermis, C (in dermis ISF) = (n/(a*b))^(3/2)/0,4 = n^(3/2)*181 [kcell/L], Where Ssection = 4mm*1,44mm=5,76mm2, Dermis ISF volume (% of Dermis volume) = 40% [21722573 ]

    4. Value [Unified unit] = e^value [Original unit] *coeff/Mw

    (4.1) Unit ID : Log_e_IU/mL-IgE

    Biological meaning of the units: Total IgE count in IU/mL in natural logarithm scale

    Value of conversion coefficient: coeff=2,4e6, Mw=190 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (4.2) Unit ID : Log_e_kU/L-Ig

    Biological meaning of the units: Total IgE count in kU/L in natural logarithm scale

    Value of conversion coefficient: coeff=2,4e6, Mw=190 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (4.3) Unit ID: Log_e_mg/dL,

    Biological meaning of the units: concentration of a particular molecule in mg/dL in natural logarithm scale

    Value of conversion coefficient : coeff=1e7

    (4.4) Unit ID: Log_e_ng/mL,

    Biological meaning of the units: concentration of a particular molecule in ng/mL in natural logarithm scale

    Value of conversion coefficient : coeff=1e3

    (4.5) Unit ID: Log_e_ug/mL,

    Biological meaning of the units: concentration of a particular molecule in ug/mL in natural logarithm scale

    Value of conversion coefficient : coeff=1e6

    5.Value [Unified unit] = 10^value [Original unit] *coeff/Mw

    (5.1) Unit ID: Log_10_kU/L-IgE

    Biological meaning of the units: Total IgE count in kU/L in 10-logarithm scale

    Value of conversion coefficient: coeff=2,4e6, Mw=190 [kDa]

    Description: [https://www.rndsystems.com/resources/technical-information/unit-conversion-table]

    (5.2) Unit ID: Log_10_mg/dL,

    Biological meaning of the units : concentration of a particular molecule in 10-logarithm scale

    Value of conversion coefficient : coeff=1e7

    (5.3) Unit ID: Log_10_ng/mL,

    Biological meaning of the units : concentration of a particular molecule in ng/mL in 10-logarithm scale

    Value of conversion coefficient : coeff=1e3

    (5.4) Unit ID: Log_10_ug/mL,

    Biological meaning of the units : concentration of a particular molecule in ug/mL in 10-logarithm scale

    Value of conversion coefficient: coeff=1e6